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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Apr 4;33(6):1350–1359. doi: 10.1161/ATVBAHA.112.300287

Figure 5. Loss of BMPRII in human coronary arteries with advanced atherosclerotic plaques.

Figure 5

(A, B) Representative confocal microscopy images of human coronary arteries containing various stages of atherosclerotic lesions were stained with antibodies to BMPRII (i-iii) and PECAM-1 (iv-vi), shown in red. DAPI (blue); auto fluorescence matrix signals (green). Images shown in (B) are magnified regions indicated by broken boxes in (A). (C) The graph shows semi-quantification of BMPRII staining intensity in the endothelial layer as a function of atheroma severity carried out by two blinded investigators (n=14).