Table 1.
Demographic and clinical characteristics
| Adjunctive catheter-directed thrombolysis (n=90) | Standard treatment only (n=99) | |
|---|---|---|
| Baseline | ||
| Age (years) | 53.3 (15.7) | 50.0 (15.8) |
| Women | 32 (35.6) | 38 (38.4) |
| Duration of symptoms of acute DVT (days) | 6.4 (4.4) | 6.8 (4.8) |
| EQ-5D index | 0.46 (0.39) | 0.63 (0.99) |
| VEINES-QOL score | 50.2 (9.3) | 50.1 (10.7) |
| VEINES-Sym score | 50.4 (9.3) | 49.5 (10.7) |
| No risk factor for venous thrombosis | 31 (34.4) | 26 (26.3) |
| Transient risk factors for venous thrombosis | ||
| Surgery previous 3 months | 15 (16.7) | 13 (13.1) |
| Trauma previous 3 months | 10 (11.1) | 15 (15.2) |
| Short-term immobility | 20 (22.2) | 19 (19.2) |
| Infection previous 6 weeks | 6 (6.7) | 9 (9.1) |
| Pregnancy previous 3 months | 5 (5.6) | 3 (3.0) |
| Hormonal replacement therapy | 4 (4.4) | 6 (6.1) |
| Oral contraceptive pill | 3 (3.3) | 11 (11.1) |
| Permanent risk factors for venous thrombosis | ||
| Previous venous thrombosis | 9 (10.0) | 9 (9.1) |
| Cancer | 3 (3.3) | 1 (1.0) |
| Obesity | 9 (10.0) | 11 (11.1) |
| Inflammatory bowel disease | 0 (0.0) | 3 (3.0) |
| First degree relative with venous thrombosis | 9 (10.0) | 13 (13.1) |
| Two risk factors for venous thrombosis | 26 (28.9) | 18 (18.2) |
| Three risk factors for venous thrombosis | 10 (11.1) | 14 (14.1) |
| Thrombophilia | ||
| Heterozygous F5 6025 polymorphism | 23 (25.6) | 22 (22.2) |
| Homozygous F5 6025 polymorphism | 1 (1.1) | 4 (4.0) |
| Other thrombophilic factor(s) | 15 (16.7) | 13 (13.1) |
Data are mean (SD) or n (%).
DVT, deep vein thrombosis; QOL, quality of life.