Table 3. SNPs associated with severe malaria in Vietnam adjusted by ethnic group.
case allele |
control allele |
HWE 10 control |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
rs number | gene | Chr | 1 | 2 | freq 16 | freq 1 | P (add7) | OR (95% CI)8 | P (gen9) | P |
rs54981 | ICAM1 | 19 | A | G | 0.80 | 0.78 | 0.039 | 0.87 (0.76-0.99) | 0.008 | 0.53 |
rs17561 | IL1A | 2 | G | T | 0.94 | 0.95 | 0.30 | 1.14 (0.90-1.44) | 0.005 | 0.02 |
rs708567 | IL17RC | 3 | A | G | 0.14 | 0.11 | 0.004 | 0.79 (0.67-0.93) | 0.016 | 0.37 |
rs205412 | IL13 | 5 | C | T | 0.62 | 0.58 | 0.007 | 0.86 (0.77-0.96) | 0.023 | 0.90 |
rs9092533 | LTA | 6 | C | T | 0.46 | 0.49 | 0.035 | 1.12 (1.01-1.25) | 0.079 | 0.36 |
rs17999644 | TNF | 6 | C | T | 0.25 | 0.23 | 0.023 | 0.86 (0.76-0.98) | 0.072 | 0.87 |
rs18006295 | TNF | 6 | A | G | 0.06 | 0.07 | 0.054 | 1.24 (0.99-1.54) | 0.027 | 0.58 |
ICAM1 codon469,
IL-13 46457,
LTA Nco1,
TNFa-1031,
TNF -308,
frequency,
the additive model,
odds ratio (95% confidence interval),
general,
Hardy Weinberg Equilibrium