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. 2013 Sep 2;3:2567. doi: 10.1038/srep02567

Figure 2. The central ISTID region is necessary for vesicle association of Nmnat2-Venus in vivo.

Figure 2

(a) Single longitudinal confocal slices of whole-mounted sciatic nerve axons showing numerous clearly identifiable vesicles in nerves from Nmnat2-Venus mice (some highlighted by arrows in each image) compared to exclusively diffuse, cytosolic staining in nerves from Nmnat2Δex6-Venus mice. Two representative images are shown for each line. (b) First frame and corresponding kymograph (time-distance graph) of representative sciatic nerve axon live imaging time series from Nmnat2-Venus and Nmnat2Δex6-Venus mice. Total time represented in kymograph is 2 minutes (240 frames at 2 fps).