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. 2013 Aug 12;2(8):e62. doi: 10.1038/oncsis.2013.22

Figure 4.

Figure 4

MyD88 deficiency decreases radiation-induced apoptosis in mouse colon following whole-body radiation. (a) Representative images of H&E-stained colon sections in MyD88-deficient and wild-type mice 4.5 h after 14 Gy whole-body radiation. (b) Representative images of consecutive DAPI, TUNEL and γ-H2ax-stained sections of colon in MyD88-deficient and wild-type mice 4.5 h after 14 Gy radiation. Blue is DAPI nuclear staining, TUNEL is green and γ-H2ax is red. In the merged image, yellow indicates colocalization of TUNEL-γ-H2ax double-positive nuclei. (c) Quantification of TUNEL-positive cells at baseline and 4.5 h post 14 Gy radiation. In all panels, means±standard error are shown, **P<0.01 MyD88-deficient versus wild-type mice.