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. Author manuscript; available in PMC: 2013 Sep 2.
Published in final edited form as: Transplantation. 2011 Apr 15;91(7):744–750. doi: 10.1097/TP.0b013e31820c85dc

Figure 2.

Figure 2

Figure 2

An increased number of Th17 cells in patients treated with sirolimus monotherapy. (A) Quantitative PCR measurement of IL-17A, RORC, IFNG and TBX21 mRNA in peripheral blood of kidney transplant recipients after 3 years of the indicated maintenance immunosuppressive treatment. Data expressed in arbitrary units calculated using the 2−ΔΔCt method normalized to HPRT expression. (B) Example CCR6+CD4+ T cells gating. (C) Frequency and absolute number of CCR6+CD4+ T cells in the peripheral blood of renal transplant recipients after 3 years of the indicated maintenance immunosuppressive treatment.