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. Author manuscript; available in PMC: 2013 Sep 2.
Published in final edited form as: Nanoscale. 2012 Jan 3;4(3):715–726. doi: 10.1039/c2nr11562j

Fig. 3.

Fig. 3

Interferometric Reflectance Imaging Sensor (IRIS). (a) Schematic of the optical setup. The setup consists of a multi-wavelength LED light source that is set up in Kohler illumination with a 50 × 0.8NA objective. The sample is imaged at a single wavelength using a CCD camera. (b) The close-up schematic of the object space where the scattered and reflected fields are shown. (c) IRIS image of immobilized virus on the surface with the same field of view as the SEM image. (d) SEM image of the immobilized virus on the surface. (e) Size distribution of single particles on different chips. (f) Measured size distribution of the immobilized virus using IRIS. Adapted from ref. 64. © 2010 American Chemical Society.