Table 3.

The liver contrast-to-noise ratio (CNR) at different IONP doses under different magnetic field strengths.

			Time
	Magnetic strength	Dose (mg/kg)	0 min	10 min	60 min	24 h	72 h	1 wk	2 wk
SMG-10	7.0T	2.5	23.19±0.55	8.30±2.34	7.24±2.41	7.45±0.45	6.72±1.34	8.03±1.87	10.02±0.73Δ
	3.0T	0.56	15.78±1.70	12.27±2.54	9.69±1.09	8.04±1.07*	10.08±3.35	11.28±1.71*	12.50±3.32
SMG-30	7.0T	2.5	22.31±2.09	5.05±1.13Δ	5.93±1.66	6.97±2.27	8.32±0.86	10.22±1.33	11.44±2.39Δ
		1.0	31.66±4.31	7.15±0.78$	7.13±0.38$	7.25±0.52$	7.11±1.27$	10.36±0.93$	12.02±0.73
	3.0T	1.0	18.71±2.74#	8.46±3.65	8.38±1.47	6.00±1.45	8.02±1.18	12.46±0.83	13.08±4.55
		0.56	19.64±0.40	9.33±0.89	7.36±1.93*	6.72±2.39*	10.37±1.51*	12.59±0.87	14.01±3.73
SHP-10	7.0T	2.5	21.06±1.94	5.93±1.66Δ	5.59±0.79	6.55±1.39	7.98±1.16	10.45±1.73	12.85±0.99
	3.0T	0.56	19.69±5.87	11.84±2.82	8.48±1.13*	7.98±0.75*	8.84±1.66*	14.56±1.58	15.62±1.34
SHP-30	7.0T	2.5	20.10±1.73	4.83±0.39Δ	4.61±0.09Δ	5.14±0.22Δ	5.93±0.54Δ	9.48±1.29	11.15±0.97Δ
		1.0	32.34±4.17	6.98±0.60	6.32±0.20	6.61±0.58	7.46±0.78$	13.81±1.81	18.26±1.74
	3.0T	1.0	20.83±1.83#	12.22±1.54	10.75±1.01	7.48±1.65	11.81±1.95	14.23±2.64	18.85±2.91
		0.56	19.78±0.89	12.67±0.26	8.52±0.28*	7.66±1.44*	9.9±2.08*	14.14±2.5	15.67±1.22
Feridex	7.0T	2.5	20.90±1.42	9.48±1.16	6.22±1.32Δ	6.94±1.30	8.48±0.65	10.97±0.72	14.77±2.20
		1.0	26.18±2.23	9.63±0.82	9.91±0.42	9.54±0.26	9.92±0.40	17.80±2.02	19.57±2.26#
	3.0T	1.0	19.50±1.63#	13.92±1.86	13.96±1.03	14.04±4.01	15.51±3.11	17.76±8.92	19.75±7.48
		0.56	16.09±2.29	10.67±2.90	10.59±0.54	13.51±2.84	14.97±2.06	15.04±1.5	16.83±3.98

^*P < 0.05 for Feridex vs. IONPs at 3.0 T and 0.56 mg Fe/kg;

^#P < 0.05 for 3.0 T vs. 7.0 T at 1.0 mg Fe/kg;

^ΔP < 0.05 for Feridex vs. IONPs at 7.0 T and 2.5 mg Fe/kg;

^$P < 0.05 for Feridex vs. SHP-30/SMG-30 at 7.0 T and 1.5 mg Fe/kg.