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. 2011 Sep 21;3(3):3676–3686. doi: 10.3390/cancers3033676

Table 1.

β-catenin Associated Genetic Mouse Models of Pancreas Cancer.

β-catenin Phenotype Ref.
Pdx1-CreLate; Ctnnb1exon3/+ Acinar cell proliferation and postnatal pancreatomegaly without tumor formation. [29]
Pdx1-CreLate; Apc flox/flox Acinar cell proliferation and postnatal pancreatomegaly without tumor formation. [30]
p48-Cre; Ctnnb1exon3/+ Development of tumors similar to human solid pseudopapillary tumors. [31]
p48-Cre;Ctnnb1exon3/+; LSL-KrasG12D Development of tumors similar to intraductal tubular tumors. [31]