Table 6.

Comparison with the state-of-the-art methods

Method	Clinical score	Data set	Result
Wang et al. 2010	MMSE	23 AD, 74 MCI, 22 NC	MMSE: RMSE=3.29, CORR=0.76
Fan et al. 2010	MMSE, ADAS-Cog	52 AD, 148 MCI, 64 NC	MMSE: RMSE=2.12, CORR=0.57
			ADAS-Cog: RMSE=5.03, CORR=0.52
Stonnington et al. 2010	MMSE, ADAS-Cog	Set1	Set1
		73 AD, 91 NC	MMSE: CORR=0.70
		Set2	Set2
		113 AD, 351 MCI, 122 NC	MMSE: CORR=0.48
			ADAS-Cog: CORR=0.57
		Set3	Set3
		39 AD, 92 MCI, 32 NC	MMSE: CORR=0.51
			ADAS-Cog: CORR=0.47
Zhang et al. 2012	MMSE, ADAS-Cog	45 AD, 91 MCI, 50 NC	MMSE: CORR=0.70
			ADAS-Cog: CORR=0.74
Our proposed method	MMSE, ADAS-Cog	51 AD, 99 MCI, 52 NC	MMSE: RMSE=1.92, CORR=0.80
			ADAS-Cog: RMSE=4.45, CORR=0.78

RMSE root mean square error, CORR correlation coefficients, MMSE mini-mental state examination, ADAS-Cog Alzheimer’s disease assessment scale-cognitive subscale