Table 1.

Effects of STZ treatment and dietary PA feeding on the food intake, bodyweight, albuminuria, biochemical parameters, serum AGE, TNFα, IL-6, GSH, and 8-hydroxy-2′-deoxyguanosine of apolipoprotein E-deficient mice.

	Control	Control + PA	Diabetic	Diabetic + PA
Initial bodyweight, g	195.13 ± 9.5	196.33 ± 6.5	196.44 ± 7	197 ± 7.2
Final bodyweight, g	265.5 ± 8.2	234 ± 12.3a,b	161.8 ± 7.2a	215.52 ± 8.9a,b
Glucose, mg/dL	92.78 ± 0.45	96.21 ± 0.57a,b	265.35 ± 1.45a	106.71 ± 1.23b
HbA1c, %	5.24 ± 0.41	6.88 ± 0.52b	9.42 ± 0.34a	6.85 ± 0.38b
Albumin, g/L	38.4 ± 5.7	38.9 ± 8.1	38.2 ± 7.7	38.7 ± 7.5
Total protein, g/L	76 ± 7	69.91 ± 7.5b	62 ± 6.5a	65.6 ± 7.1
GSH, mmol/L	0.281 ± 0.015	0.172 ± 0.02a,b	0.105 ± 0.03a	0.145 ± 0.021a,b
Catalase, U/g Hb	94.54 ± 14	86.55 ± 12b	50.98 ± 15a	70.11 ± 11a,b
Glutathione reductase, U/gHb	4.25 ± 0.09	3.21 ± 0.94b	2.25 ± 0.62a	2.54 ± 0.54a,b
Glutathione peroxidase, U/gHb	57.1 ± 11	69.9 ± 9.55b	145.5 ± 45a	89.54 ± 10.2b

Data shown represent mean ± SE of mice, 12 weeks after the treatment with STZ or with the buffer (control) in presence or absence of PA. ^a,bSignificance difference between groups.