Table 2.
Area under the curve (AUC) for insulin levels under 2 mM basal glucose (KRB2) followed by stimulation with 30 mM KCl, 150 µM TB, 10 mM KIC, and again under KRB2 in human islets (100 islets) from different human pancreatic isolation batches. These are results from single representative experiments for each isolation batch.
AUC-30 mM KCl | AUC-150 µM TB | AUC-10 mM KIC | |||||||
---|---|---|---|---|---|---|---|---|---|
Batch # | KRB2 | KCl | KRB2 | KRB2 | TB | KRB2 | KRB2 | KIC | KRB2 |
2 | 23.96 | 370.20 | 18.38 | 17.86 | 42.93 | 5.38 | ND | ND | ND |
3 | 12.33 | 312.60 | 13.47 | 29.03 | 168.50 | 9.57 | ND | ND | ND |
4 | 31.22 | 108.00 | 11.81 | 0.00 | 16.07 | 28.37 | 7.06 | 53.37 | 2.53 |
5 | 1.03 | 440.10 | 40.36 | 0.14 | 167.50 | 5.58 | 1.11 | 145.90 | 18.70 |
6 | 0.85 | 30.01 | 0.76 | 0.17 | 73.61 | 7.51 | ND | ND | ND |