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. Author manuscript; available in PMC: 2013 Sep 2.
Published in final edited form as: J Neurophysiol. 2007 Oct 3;98(6):3121–3133. doi: 10.1152/jn.00904.2007

Figure 7.

Figure 7

Systemic administration of 0.5 mg morphine reduced withdrawal amplitude (traces marked EMG) but did not excite this murine off cell. A–C: Average responses (250 ms bins, top traces) to repeated trials of heat stimulation (bottom traces) during the baseline period (A, n=3 trials), after 0.5 mg morphine administration (B, n=3), and after naloxone (0.4 mg; C, n=2). D: The full-length recording from this cell with the rectified integrated EMG (top) and the instantaneous discharge (bottom) for the entire duration of the experiment (~1 hr). Tail heat stimulation was applied regularly throughout the recording at the times marked by the arrowheads. The time points at which morphine and naloxone were injected are indicated by M and N, respectively. The scale bar in C applies to the records in A–C. The scale bar beneath D applies to D only.