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. 2013 Sep 2;8(9):e72295. doi: 10.1371/journal.pone.0072295

Figure 4. Correlation of superinfection with the percentage of CD4+ Tcm cells in CD3+ T cells from GUT prior to SHIV-1157ipd3N4 inoculation.

Figure 4

(A) Percentages of CD4+ T cells in CD3+ T cells from PBL, LN and GUT in SIR monkeys (black bars) and SIS monkeys (red bars) (Mann-Whitney U test, *P = 0.0260). (B) Percentages of CD4+ Tcm cells in CD3+ T cells from PBL, LN and GUT in SIR monkeys (black bars) and SIS monkeys (red bars) (Mann-Whitney U test, *P = 0.0087). (C) Percentages of CD4+ Tcm cells or CD4+ Tem cells in CD3+ T cells from GUT in SIR (black bars) and SIS monkeys (red bars) (Mann-Whitney U test, *P = 0.0087). (D) Correlation between the AUC of SHIV-1157ipd3N4 viremia following superinfection and the percentage of gut-derived CD4+ Tcm cells in CD3+ T cells prior to SHIV-1157ipd3N4 inoculation (Pearson's correlation test, R = 0.682, *P = 0.0146). All the samples were obtained prior to SHIV-1157ipd3N4 inoculation (on day 540 after primary infection).