Skip to main content
. 2013 Sep 2;8(9):e73161. doi: 10.1371/journal.pone.0073161

Figure 3. qPCR of ECFCs and primed ECFCs under static and cyclic strain in 3D.

Figure 3

Expression of ECM genes is shown relative to primed ECFCs before seeding into the 3D gels. (A) Cyclic strain significantly decreased expression of collagen type I and III in ECFCs for all medium groups. The expression of collagen IV was not detected. (B) Cyclic strain significantly upregulated expression of collagen type I and III in ECFCs primed with TGFβ1. Elastin expression was reduced in these cells in response to cyclic strain. * = p<0.05, ** = p<0.01, N = 3.