Table 2. Prediction of transcription factor binding sites of NF-κB and p38-dependent genes using opossum.
TF§ | TF Class | Background TFBS rate† | Target TFBS rate | Z-score | |||
RELA (p65) | REL | 0.0043 | 0.0152 | 17.64 | |||
REL | REL | 0.0094 | 0.0241 | 16.04 | |||
NFKB1 | REL | 0.0028 | 0.0108 | 15.98 | |||
NF-κB (p50) | REL | 0.0061 | 0.0152 | 12.27 | |||
DDIT3-C/EBPα | bZIP | 0.0036 | 0.0086 | 8.55 | |||
C/EBPα | bZIP | 0.0114 | 0.0193 | 7.80 | |||
HLF# | bZIP | 0.0048 | 0.0096 | 7.27 | |||
SRF# | MADS | 0.0005 | 0.0021 | 7.19 | |||
USF1# | bHLH-ZIP | 0.0083 | 0.0144 | 6.95 | |||
SOX9 | High Mobility Group | 0.0115 | 0.0185 | 6.87 |
TF: transcription factor.
Background TFBS rate: rate of transcription factor binding site in genome.
TF Abbreviation: HLF: hepatic leukemia factor; SRF: serum response factor; USF1: Upstream stimulatory factor 1.