Table 2. Down regulation of UPS associated genes by NOD.

Gene	Fold change (log2)a	p-valueb
Ubiquitin ligases
UBE2L6	2,04	5,8E-11
HERC6	2,48	2,1E-12
Ubiquitin like
UBD	5,60	2,1E-22
ISG15	2,68	3,7E-15
Proteasome
PSME1	1,55	6,8E-12
PSMB10	1,75	7,0E-12
PSMB8	1,96	3,1E-11
PSMB9	3,46	2,2E-10

^afold change values are expressed as Log2, TNF-α compared to TNF-α plus 100 µM NOD.

^b p-values for the comparison TNF-α vs. TNF-α plus 100 µM NOD are given as log10.