Table 2.

IMQ-induced skin inflammation in mice phenotypically resembles psoriasis. C57BL/6 mice were treated daily for 5 days with IMQ suspension on the shaved back skin and then the inflamed area was treated with CyLiPn formulations (C-CyLiPn, S-CyLiPn and CS-CyLiPn); CS-Solution; and Topgraf^®. Psoriasis Area and Severity Index (PASI) score of the back skin was recorded daily on a scale from 0 to 4. Data represent mean ± SD (n=6).

Day	Normal	IMQ	S-CyLiPn	C-CyLiPn	CS-CyLiPn	Topgraf®	C-Solution
1	0 ± 0	4 ± 0	4 ± 0	4 ± 0	4 ± 0	4 ± 0	4 ± 0
2	0 ± 0	4 ± 0	3 ± 0.55	3 ± 0.51	2 ± 0.55	1 ± 0.51	3 ± 0.41
3	0 ± 0	4 ± 0	2 ± 0.52	3 ± 0.41	2 ± 0.41	1 ± 0.41	3 ± 0.51
4	0 ± 0	4 ± 0	2 ± 0.52	3 ± 0.41	1 ± 0.51	0 ± 0.51	3 ± 0.51
5	0 ± 0	4 ± 0	2 ± 0.41	2 ± 0.55	0 ± 0.41	0 ± 0.41	3 ± 0.55