Table 2.

Multivariable regression analysis predicting white matter disease volume^*

Variable	Relative Difference in White Matter Disease Volume† (95% Confidence)	p-value
Presence of coronary plaque	1.49 (1.00–2.23)	0.05
Female sex	1.99 (1.32–.00)	0.001
Black race	1.29 (0.87–92)	0.21
Hypertension	1.51 (1.03–2.21)	0.03
Diabetes	0.78 (0.45–1.33)	0.36
Current smoking	1.17 (0.74–1.85)	0.49
	Log Scale Beta ± SE
Age	0.093 ± 0.010	<0.001
LDL cholesterol	−0.003 ± 0.002	0.17

^*Adjusted for intrafamilial correlation (GEE) and total brain volume

^†Geometric mean