Table 4. Logistic regression analysis of tapasin G with specific amino acid residues at the three different HLA class I loci and the outcome of infection.
An OR >1 indicates a positive association with resolution
| a) HLA-A | |||
|---|---|---|---|
| p | OR | 95% CI | |
| Tapasin G | 0.001 | 2.29 | 1.42–3.70 |
| Tapasin G+ Arg 156 | p>0.1 | ||
| Arg 156 | p>0.1 | ||
| b) HLA-B | |||
|---|---|---|---|
| p | OR | 95% CI | |
| Tapasin G | 0.001 | 2.72 | 1.75–5.04 |
| Tapasin G+ Asp114 | 0.027 | 3.00 | 1.13–7.93 |
| Tapasin G+ Asp156 | 0.048 | 2.79 | 1.01–7.68 |
| Asp156 | 0.053 | 0.61 | 0.37–1.01 |
| Asp114 | 0.079 | 0.65 | 0.40–1.05 |
| Tapasin G+ Ser116 | >0.1 | ||
| Ser116 | >0.1 | ||
| c) HLA-C | |||
|---|---|---|---|
| p | OR | 95% CI | |
| Tapasin G | <0.001 | 2.33 | 1.45–3.74 |
| Asp114 | 0.002 | 2.43 | 1.39–4.25 |
| Ser116 | 0.006 | 0.51 | 0.31–0.82 |
| Tapasin G+ Ser116 | 0.011 | 3.48 | 1.32–9.13 |
| Tapasin G+ Asp114 | 0.058 | 0.34 | 0.11–1.04 |