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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: Neuroimage. 2013 Jun 5;0:87–100. doi: 10.1016/j.neuroimage.2013.05.118

Figure 9. PCC functional connectivity determined by RSMFC and GSReg.

Figure 9

Voxels that have positive correlation with the PCC are colored red and voxels that have negative correlations are colored blue. For positive correlations, both methods yield similar spatial patterns in DMN networks, except that RSMFC reveals left and right MTL nodes missed by GSReg (slice at Z = −10). Critically, negative correlations identified by GSReg (shown in blue) are much more widespread than in RSMFC. Both connectivity maps are thresholded using a voxel-wise height threshold of p < 0.001 and a spatial extent threshold of 42 voxels, corresponding to an overall p < 0.01 for a family-wise error correction. PCC = posterior cingulate cortex. DMN = default mode network. AG = angular gyrus. mPFC = medial prefrontal cortex. MTL = medial temporal lobe. RSMFC = random subspace method functional connectivity. GSReg = global signal regression method.