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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Nitric Oxide. 2013 May 14;0:18–41. doi: 10.1016/j.niox.2013.05.001

Fig. 12.

Fig. 12

Effects of 5,14-HEDGE and 20-HEDE on changes in 6-keto-PGF1α levels in (A) kidney, (B) heart, (C) thoracic aorta, and (D) superior mesenteric artery measured 4 h after saline (vehicle) (4 ml/kg, i.p.) or LPS (10 mg/kg, i.p.) injection to conscious rats. 5,14-HEDGE (30 mg/kg, s.c.) and/or 20-HEDE (30 mg/kg, s.c.) were given 1 h after administration of saline or LPS. 6-keto-PGF1α levels in tissue homogenates were measured by the 6-Keto-PGF1α ELISA Kit following the manufacturer’s instructions. Data are expressed as means ± S.E.M of 4 animals. aSignificant difference from the corresponding value seen in rats treated with saline (p < 0.05). bSignificant difference from the corresponding value seen in the rats treated with LPS (p < 0.05). cSignificant difference from the corresponding value seen in the rats treated with LPS and 5,14-HEDGE (p < 0.05).