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. 2013 Aug 15;27(16):1809–1820. doi: 10.1101/gad.221341.113

Figure 6.

Figure 6.

Endogenous Paip2 functions to restrict productive HCMV growth when the virus-induced PABP accumulation is blocked. (A) NHDFs transfected with a control nonsilencing siRNA (ctrl) or the indicated pairs of siRNAs were infected with HCMV (MOI = 0.1) and imaged for EGFP expression 5 d post-infection. (B) Supernatants collected from three independent experiments detailed in A were assayed for viral particle production based on their TCID50 (Heider et al. 2002). Error bars indicate standard error of the mean. (*) P < 0.022 for control versus PABP1 siRNA; (**) P < 0.01 for PABP1 versus PABP1/Paip2 siRNA. Control versus Paip2 was not statistically significant (P > 0.1).