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. 2013 Sep 3;4:111. doi: 10.3389/fphar.2013.00111

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Copyright © Kaufman, Gordon, Bergamaschi, Wang, Cohen, Valiunas and Brink.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Macroscopic properties of gap junction channels. (A) Gap junction currents (I_j) elicited from HEK-293 cells by bipolar V_j pulses (V₁ and V₂; top panel) in control pairs (left panel) and cell pairs with 4-PB exposure (right panel). (B) Average of gap junction conductance for 4-PB treated (22.7 ± 1.7 nS, n = 31 cell pairs) and control (16.9 ± 1.8 nS, n = 32 cell pairs), p = 0011.