Table 1.

Function of NAC transcription factors in biotic infections.

Genes/target genes	Functions	Method	Species	References
HvNAC6	HvNAC6 positively regulates penetration resistant toward Bl. gramini f.sp. hordei (Bgh) attack	Knockdown/overexpression	H. vulgare	Jensen et al., 2007
ataf1-1	Loss-of-function mutants have attenuated penetration resistance toward Bgh attack	Knockout	A. thaliana (At)	Jensen et al., 2008
ATAF1, PR1	ATAF1 negatively regulates resistance to B. cinerea	Overexpression/ataf1-1 and ataf1-2, knockout	A. thaliana	Wu et al., 2009
ATAF1, PR-1, PR-5, NPR1, PDF1.2	ATAF1 negatively regulates resistance to P. syringae, B. cinerea, A. brassicicola	Overexpression/ataf1-2, knockout	A. thaliana	Wang et al., 2009a
ATAF2, PR1, PR2, PR4, PR5, PDF1.1, PDF1.2	ATAF2 negatively regulates resistance to F. oxysporum, represses pathogenesis-related proteins	Overexpression/knockout	A. thaliana	Delessert et al., 2005
ATAF2, PR1, PR2, PDF1.2	OX = Reduced tobacco mosaic virus accumulation, increased pathogenesis-related genes	Overexpression/knockout	A. thaliana	Wang et al., 2009a
ATAF2, NIT2	Defense hormones, pathogen infection	Overexpression/knockout	A. thaliana	Huh et al., 2012
ANAC019, ANAC055	Defense disease, JA pathway	Overexpression	A. thaliana	Bu et al., 2008
NTL6, PR1, PR2, PR5	Positive regulator of pathogen resistance against P. syringae	Gene silencing/overexpression	A. thaliana	Seo et al., 2010
ANAC042, P450	Regulation of camalexin biosynthesis, pathogen infection	β - Glucuronidase (GUS)-reporter assays	A. thaliana	Saga et al., 2012
SlNAC1	Increased tomato leaf curl virus (TLCV) DNA accumulation	Transient overexpression	N. benthamiana	Selth et al., 2005
OsNAC4	Inducer of HR cell death upon Acidovorax avenae infection, loss of plasma membrane integrity, nuclear DNA fragmentation	Overexpression/knockdown	Oryza (O) sativa	Kaneda et al., 2009
OsNAC6, PR protein 1, Probenazoleinducible proteins (PBZ1s), DUF26- like Ser/Thr protein kinase, Thioredoxin, Peroxidase, Lipoxygenase,	Slightly increased tolerance to rice blast disease	Overexpression	O. sativa	Nakashima et al., 2007
rim1-1	Resistance to rice dwarf virus (RDV), susceptible to rice transitory yellowing virus (RTYV) and RSV	Knockout	O. sativa	Yoshii et al., 2009
Os02g34970, Os02g38130, Os11g03310, Os11g03370, Os11g05614, Os12g03050	RSV, RTSV infections	Microarray	O. sativa	Nuruzzaman et al., 2010
OsNAC19	Disease resistance	Infection	O. sativa	Lin et al., 2007
GRAB1, GRAB2	Inhibited wheat dwarf virus replication	Transient Overexpression	T. monococcum	Xie et al., 1999
ATAF2	Tobacco mosaic virus	Transgenic	Tobaco	Wang et al., 2009b
ONAC122 and ONAC131 brome mosaic virus (BMV)	Defense responses against Magnaporthe grisea	–	O. sativa	Sun et al., 2013
SlNAC1	Upregulated during pseudomonas infection	Pathogen infection	S. lycopersicum	Huang et al., 2012
CaNAC1	Defense responses against pathogen	Infection	C. arietinum	Oh et al., 2005
GmNAC6	Responses to biotic signals, osmotic stress-induced	Transctiption	G. max	Faria et al., 2011
TLCV, SlNAC1	Enhances viral replication	Overexpression	L. esculentum	Selth et al., 2005
BnNAC14, BnNAC485, ATAF1 or ATAF2	Response to biotic and abiotic stresses including wounding	cDNA libraries	–	Hegedus et al., 2003
Stprx2, StNAC	Wounding and pathogen response	Transcriptome	S. tuberosum	Collinge and Boller, 2001
NT L4	ROS under abscisic acid, leaf senescence	Transgenic	A. thaliana	Lee et al., 2012
NTL9	Osmotic stress responses, leaf senescence	Overexpression/knocout	A. thaliana	Yoon et al., 2008
MtNAC969	Symbiotic nodule senescence	Overexpresion	M. truncatula	de Zélicourt et al., 2012
VNI2, OR/RD	Leaf senescence	Transcription	A. thaliana	Seo and Park, 2011
Os07g37920, Wheat GPC	Senescence	Overexpression/RNAi	O. sativa, T. aestivum	Distelfeld et al., 2012
AtNAP	Leaf senescence	Overexpression/RNAi	A. thaliana	Guo and Gan, 2006