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. 2013 Sep;93(5):538–547. doi: 10.1016/j.tube.2013.05.002

Figure 6.

Figure 6

Reduced IL-1β and TNF-α secretion from M. tuberculosis infected macrophages in the presence of some serine protease inhibitors. M. tuberculosis infected macrophages were treated with 50 μM TPCK, 50 μM TLCK and 20 μM caspase-1 individually or in tandem. Cytokine concentrations for IL-1β (A) and TNF-α (B) were analysed in the supernatants by ELISA at 48 h. The absolute values of cytokines are expressed as a fold change over control strains. Data represents mean ± SD of two independent experiments.