Table 2.

The effect of diabetes and GLO-1 overexpression on several parameters of cardiac remodeling. Gene expression values are given as percentage from control.

Characteristic	Control	Diabetes	Diabetes + GLO-I
Cardiac Hypertrophy	(C)	(D)	(DG)
Cardiac weight (g)	1.32 ± 0.08	1.080 ± 0.05 *	0.993 ± 0.04 **
Heart/bodyweight (%)	0.276 ± 0.01	0.360 ± 0.01 ***	0.333 ± 0.01 **
ANP (% from C)	100 ± 15	499 ± 139 **	385 ± 48 ***
BNP (% from C)	100 ± 16	148 ± 23 *	157 ± 13 **
Cardiomyocyte CSA (μm3)	277 ± 12	284 ± 21	260 ± 21
Ventricular Dimensions	-	-	-
Thickness wall diastole (cm)	0.17 ± 0.01	0.14 ± 0.01 **	0.15 ± 0.01 *
Volume wall diastole (cm3)	0.49 ± 0.03	0.40 ± 0.03 *	0.45 ± 0.02
Internal diameter cavity diastole (cm)	0.84 ± 0.06	0.84 ± 0.05	0.77 ± 0.04 **
Thickness wall systole (cm)	0.19 ± 0.01	0.17 ± 0.01 **	0.17 ± 0.01 *
Volume wall systole (cm3)	0.43 ± 0.03	0.39 ± 0.02	0.40 ± 0.02
Internal diameter cavity systole (cm)	0.68 ± 0.06	0.70 ± 0.04	0.64 ± 0.04

^*p < 0.05 compared with control,

^**p < 0.01 compared with control,

^***p < 0.001 compared with control.