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. 2013 Aug 5;14(8):16087–16110. doi: 10.3390/ijms140816087

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Expression of 17 filtered miRNAs in different cell populations. The heat map visualizes the levels of IFN-beta-responsive miRNAs in 19 blood cell populations and four brain tissues. The data were downloaded from the smirnaDB database [64], which did not contain three of the 20 filtered miRNAs (hsa-miR-27a-5p, hsa-miR-29b-1-5p and hsa-miR-181c-3p). hsa-let-7a-5p and hsa-miR-16-5p are highly expressed in peripheral blood and brain. hsa-let-7b-5p and hsa-miR-149-5p are preferentially expressed in brain tissues. Several of the miRNAs (e.g., hsa-miR-346) were not detected in certain cell types [65].