Table 1.

Clinical data and demographic data of the patients.

Patient	Type	Age	Disease duration	EDSS (baseline)	EDSS (1 year)	Relapses (1 year)
Pat1	CIS	28	1	1.0	1.0	0
Pat2	RRMS	38	2	1.5	1.5	0
Pat3	RRMS	22	1	1.5	1.0	0
Pat4	RRMS	50	12	2.5	2.5	0
Pat5	CIS	60	2	1.5	2.5	0
Pat6	RRMS	27	2	2.0	1.0	2

Six female patients were recruited for the main cohort of this study. They were diagnosed with relapsing-remitting MS (RRMS) or clinically isolated syndrome (CIS) suggestive of MS. The age at study onset (in years) and the duration from the diagnosis to the start of IFN-beta-1b sc. therapy (in months) are shown. Additionally, the EDSS scores before treatment initiation (baseline) and after one year, as well as the number of relapses during the first year of clinical follow-up are given in the table.