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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Anal Chem. 2013 Jul 23;85(15):7542–7549. doi: 10.1021/ac401569j

Figure 4. Nrf2 activators screening by high-throughput imaging.

Figure 4

(A) High-throughput screening of Nrf2-Keap1 sensor system by different Nrf2 activators, (B) Quantified data for FLuc bioluminescence of Nrf2-Keap1 sensor system by various Nrf2 activators exposure at optimal concentrations, Photon flux data is normalized to the total protein per well and represented as percentage change. Data are shown as means ± SD (n=4: *p<0.05, **p<0.001 vs control). (C) Effect of Nrf2 activators on cell viability in HEK293TNKS cells. Data are shown as means ± SD (n=4: *p<0.05, **p<0.001 vs control).