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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Clin Cancer Res. 2012 Aug 21;18(20):5761–5772. doi: 10.1158/1078-0432.CCR-12-1182

Table 2.

Results of experimental binding studies to HLA-A3 and related supertype family HLA alleles for mutated peptides E255K-A and E255K-B. Dashed lines indicate IC50>70,000 nM.

HLA-A03 supertype binding capacity (IC50 nM)
Peptide Sequence A*0301 A*1101 A*3001 A*3101 A*3301 A*6801
E225K-A WT KLGGGGQYGE 2283 2281 10112 9871 63631 4205
MUT KLGGGQYGK 208 1074 27784 31762 -- 57106
E225K-B WT EVYEGVWKK 1074 63 -- -- 60 10
MUT KVYEGVWKK 17 39 603 202 42860 45