Table 2.

Univariate Sensitivity Analyses for Mammography Every 3 to 4 Years Versus No Mammography^*

Variable	Value Range	Cost per QALY Gained $
		Low Value	High Value
Breast cancer costs	50% to 150% of base-case values	74 765	65 856
Incidence of invasive breast cancer	70% to 130% of base-case values	101 478	50 534
Invasive breast cancer mortality	70% to 130% of base-case values	86 857	58 467
Incidence of ductal carcinoma in situ	50% to 150% of base-case values	43 840	93 571
Mammography cost	$78 to $138	55 774	91 807
Disutility of invasive breast cancer	50% to 150% of base-case values	77 792	56 150
Proportion of false-positive mammography results	1% to 10%	54 015	98 566
Disutility of false-positive mammography results	0 to 0.013 QALY	72 184	118 798
Overdetection of invasive breast cancer	0% to 10%	72 184	108 432
Stage proportion change†	Local, 0.078 to 0.178; regional, −0.054 to −0.154	104 720	54 048

QALY = quality-adjusted life-year.

^*In patients aged 50–59 y with Breast Imaging Reporting and Data System category 1 breast density.

^†Proportions of local and regional breast cancer were changed by 0.05 in opposite directions, resulting in lower or higher stage shifts.