FIG. 1.

Data source options of ZEOGS. (A) Filtering by the existence of an anatomical term: When this option is selected, the program tests which anatomical terms are present at the input stage. This option is predictive of where genes are expressed based on the current knowledge but may not be empirically based at each particular stage. (B) Filtering by actual observations of gene expression in an anatomical term: The selection of this option forces the program to consider only the anatomical terms with direct empirical evidence for a certain gene to be expressed in these anatomical structures at the selected stage, making the results of the program fully empirically based.