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Following treatment of hDFs with Pdx1, Romi, and 5AzC, the Gcg, Ins, and Pdx1 promoter regions are more acetylated. Chromatin immunoprecipitation for acetylated histones H3 and H4 in hDFs undergoing the reprogramming protocol. Values are the mean±S.E. from three separate experiments, each analyzed in duplicate. *, statistical significance compared to hDF control levels with P<0.05 value using a Student's t-test.
