FIG. 5.

Musculoaponeurotic fibrosarcoma oncogene homolog B (MafB) and glucagon expression overlap and silencing of MafB results in more insulin and less glucagon expression. (a) Quantification from immunofluorescence staining of the sorted cells described in Figure 4a. Data shown as % of cells stained positive for each protein tested or a combination of glucagon and TF. (b) Quantitative real-time PCR of hDFs under the reprogramming protocol or silenced for MafB before the reprogramming protocol. Values are the mean±S.E. from three separate experiments. *, statistical significance with P<0.05 value using a Student's t-test.