Table 1.
% Methylation | ||||||
---|---|---|---|---|---|---|
Promoter region | −234 | −206 | −180 | −135 | −102 | −69 |
β-cells | 61 | 61 | 43 | 52 | 13 | 65 |
Dedifferentiates islets | 96 | 46 | 38 | 88 | 38 | 92 |
At least 20 bisulfite sequencing of the insulin proximal promoter in islet β-cells and dedifferentiated islets. Values are the percentage of DNA methylation within the different positions of CpG sites.