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Methylation State of the Ins Promoter in hDFs and hDFs After the Reprogramming Protocol
| % Methylation | ||||||
|---|---|---|---|---|---|---|
| Promoter region | −234 | −206 | −180 | −135 | −102 | −69 |
| hDFs | 100 | 100 | 91 | 89 | 58 | 91 |
| Pdx1+Romi+5AzC | 96 | 89 | 97 | 85 | 14 | 76 |
At least 20 bisulfite sequencing of the insulin proximal promoter in control hDFs and hDFs after the reprogramming protocols. Values are the percentage of DNA methylation within the different positions of CpG sites.
