Table 2.
Patients' characteristics by categorized MCA stenoocclusion.
| MCA stenoocclusion | P value | ||||
|---|---|---|---|---|---|
| 0–49% n = 615 |
50%–69% n = 111 |
70%–99% n = 69 |
100% n = 182 |
||
| Age, years# | 59.97 ± 11.04 | 62.44 ± 11.67 | 63.01 ± 11.60 | 57.33 ± 11.22 | 0.0001 |
| Male | 438 (71.22) | 81 (72.97) | 51 (73.91) | 146 (80.22) | 0.1202 |
| Duration between symptom onset and blood tests&, day | 3 (1–5) | 3 (1–5) | 3 (1–5) | 3 (1–5) | 0.7268 |
| Duration between symptom onset and MRI procedure&, day | 6 (4, 8) | 6 (4, 9) | 7 (5, 8) | 7 (4, 9) | 0.0767 |
| Previous mRS score | 0.1801 | ||||
| 0 | 506 (82.28) | 89 (80.18) | 48 (69.57) | 147 (80.77) | |
| 1 | 85 (13.82) | 18 (16.22) | 14 (20.29) | 26 (14.29) | |
| 2 | 24 (3.90) | 4 (3.60) | 7 (10.14) | 9 (4.95) | |
| History of, yes (n, %) | |||||
| Previous cerebral ischemia, TIA, ICH, or SAH | 152 (24.72) | 29 (26.13) | 28 (40.58) | 57 (31.32) | 0.0206 |
| Hypertension | 494 (80.33) | 98 (88.29) | 57 (82.61) | 139 (76.37) | 0.0899 |
| Diabetes mellitus | 253 (41.14) | 58 (52.25) | 34 (49.28) | 64 (35.16) | 0.0188 |
| Hyperlipidemia | 504 (81.95) | 94 (84.68) | 57 (82.61) | 147 (80.77) | 0.8626 |
| Current smoking | 308 (50.08) | 50 (45.05) | 24 (34.78) | 102 (56.04) | 0.0181 |
| Heavy-to-severe drinking | 136 (22.11) | 28 (25.23) | 15 (21.74) | 41 (22.53) | 0.9083 |
| Ischemic heart disease | 70 (11.38) | 11 (9.91) | 7 (10.14) | 15 (8.24) | 0.6731 |
| NIHSS score on admission& | 4 (1, 7) | 4 (1, 7) | 3 (1, 8) | 7 (2, 11) | <0.0001 |
| NIHSS score at discharge& | 2 (0, 4) | 2 (0, 4) | 2 (1, 5) | 4 (1, 8) | <0.0001 |
| Peripheral level of inflammatory mediators | |||||
| WBC#, ×109/L | 6.89 ± 1.90 | 6.80 ± 1.94 | 6.50 ± 1.75 | 7.20 ± 2.20 | 0.0583 |
| HCY#, μmol/L | 17.52 ± 7.29 | 17.56 ± 6.58 | 17.21 ± 6.57 | 18.78 ± 8.31 | 0.2325 |
| hs-CRP&, mg/L | 2.4 (0.9, 6.7) | 2.75 (0.8, 9.5) | 2.1 (0.7, 7.2) | 3.8 (1.1, 0.2) | 0.0580 |
| Other laboratory findings on admission | |||||
| Hgb#, g/L | 141.84 ± 18.21 | 141.24 ± 18.47 | 139.25 ± 14.08 | 144.10 ± 15.67 | 0.2094 |
| PLT#, ×109/L | 214.67 ± 56.11 | 212.95 ± 60.36 | 202.15 ± 41.93 | 211.70 ± 57.98 | 0.3657 |
| FBG#, mmol/L | 5.92 ± 2.27 | 6.21 ± 2.32 | 6.26 ± 2.16 | 5.78 ± 1.94 | 0.2566 |
| Cr#, μmol/L | 78.27 ± 33.06 | 79.83 ± 22.80 | 76.84 ± 23.25 | 79.06 ± 21.62 | 0.9094 |
| INR# | 0.98 ± 0.08 | 1.00 ± 0.35 | 0.97 ± 0.05 | 0.97 ± 0.05 | 0.3831 |
| HDL#, mmol/L | 1.15 ± 0.28 | 1.11 ± 0.31 | 1.05 ± 0.23 | 1.08 ± 0.25 | 0.0038 |
| LDL#, mmol/L | 2.76 ± 0.80 | 2.75 ± 0.83 | 2.77 ± 0.95 | 2.75 ± 0.92 | 0.9987 |
| Recurrent stroke, yes | 17 (2.76) | 6 (5.41) | 5 (7.25) | 6 (3.30) | 0.1649 |
| one-year mRS | |||||
| 0–2 | 471 (79.16) | 78 (70.27) | 44 (63.77) | 111 (62.71) | <0.0001 |
| 3–6 | 124 (20.84) | 33 (29.73) | 25 (36.23) | 66 (37.29) | |
#Continuous variables with normal distribution expressed as mean ± standard deviation.
&Continuous variables with nonnormal distribution expressed as interquartile range (IQR).
Other values were expressed as n (%).
SAH: subarachnoid hemorrhage; ICH: intracerebral hemorrhage; NIHSS: National Institute of Health Stroke Scale; WBC: white blood cell; Hgb: hemoglobin; PLT: platelet; FBG: free blood glycemia; Cr: creatinine; INR: international normalized ratio; HCY: homocysteine; hs-CRP: high sensitivity C-reactive protein; HDL: high-density lipoprotein; and LDL: low-density lipoprotein.