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. 2013 Aug 15;69(Pt 9):1717–1725. doi: 10.1107/S0907444913016284

Table 2. Amino-acid preferences in the binding grooves of BIR2 and BIR3.

Data adapted from Franklin et al. (2003) and Sweeney et al. (2006).

  P1 P2 P3 P4
BIR2 Ala >> Ser Smaller aromatic or Pro Ala > Arg/Lys/Val Val/Ala/Ile/Gly
BIR3 Ala >> Val Lys/Arg > branched aliphatic Pro >> Arg Ala Phe/Tyr > Ile/Leu