Table 1.

Dicer-CKO phenotypes in the cortex and retina.

Cre transgene	Cre expression	Main phenotype	Reference
Cortex
Foxg1-Cre	From E8 in most forebrain cells	Altered balance of apical and basal progenitors	Nowakowski et al. (2011)
Emx1-Cre	From E10 to E10.5 in most cells of the dorsal telencephalon	Overproduction of early-born neurons and reduced number of Brn1-expressing upper-layer neurons	Kawase-Koga et al. (2009)
Nestin-Cre	From E10 to E10.5 in forebrain stem cells and progenitors	Affected late-born neuron generation and migration	De Pietri Tonelli et al. (2008)
CamKII-Cre	From E15.5 in post-mitotic neurons of the cortex and hippocampus	Normal layering; reduced dendritic branch elaboration	Davis et al. (2008)
Retina
Chx10-Cre	Mosaic pattern, from E14.5 in progenitors of all retinal layers	Decreased ERG responses, retinal disorganization, progressive retinal degeneration from P16	Damiani et al. (2008)
αPax6-Cre	Peripheral retina from day E10.5; differentiated amacrine cells, by E14.5	Overproduction of ganglion cells, failure to generate late cell types such as Müller glia and rod photoreceptors	Georgi and Reh (2010)
Dkk3-Cre	From E10.5 in progenitors of all neuroretinal cell types	Microphthalmia, massive apoptosis	Iida et al. (2011)
Rx-Cre	Ubiquitously in the developing neuroretina and optic stalk; later in the optic chiasm	Microphthalmia, massive apoptosis, defects in retinal ganglion cell axon pathfinding	Pinter and Hindges (2010)