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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Immunol Rev. 2010 May;235(1):234–243. doi: 10.1111/j.0105-2896.2010.00898.x

Fig. 4. Rapamycin improves the quantity and quality of memory CD8+ T cells.

Fig. 4

(A) Without rapamycin treatment. (B) Rapamycin treatment during T-cell expansion phase. Rapamycin increases memory precursor effector cells that survive during the contraction phase. Higher quantity of memory T cells is formed compared to control. (C) Rapamycin treatment during T-cell contraction phase. Rapamycin accelerates effector to memory T-cell formation, and improves quality of memory T cells. (D) Rapamycin treatment during both the expansion and contraction phase. Rapamycin improves both quality and quantity of memory CD8+ T cells.