Table 1.
Description of liposomal preparations
| Study | Formulation type | Lipid Composition | Nanoparticle sizes * (nm) |
Imaging moiety |
|---|---|---|---|---|
| In vitro optical imaging |
Non-PEG | DPPC:Chol:DPPG:Rh- DHPE – 44.9:35:20:0.1 |
100, 200, or 400 | Rhodamine |
| PEG | DPPC:Chol:mPEG-2000- DSPE:Rh-DHPE – 61.9:35:3:0.1 |
100, 200, or 400 | Rhodamine | |
| In vitro CT imaging |
Non-PEG | DPPC:Chol:DPPG 45:35:20 |
100, 200, or 400 | Iodine |
| PEG | DPPC:Chol:mPEG-2000- DSPE – 62:35:3 |
100, 200, or 400 | Iodine | |
| In vivo CT imaging |
Non-PEG | DPPC:Chol:DPPG 45:35:20 |
400 | Iodine and rhodamine |
*
the numbers 100, 200 and 400 indicate pore sizes of filter membranes through which the liposomes were extruded