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Affinities of CX4-M1 to gp120 and V3 loop peptides, respectively, from X4 tropic and R5-tropic HIV-1.
| HIV-1 strain (tropism) | KD (gp120) | KD (V3 loop peptide) |
|---|---|---|
| IIIB (X4) | 0.1 μM | 1.1 μM |
| HxBc2 (X4) | 0.2 μM | 0.3 μM |
| MN (X4) | 0.7 μM | 1.6 μM |
| ADA (R5) | No binding | No binding |
| BAL (R5) | No binding | No binding |
