TABLE 1.
Table showing the tested alleles from Figure 1 and Dimova et. al. compared with the effects of halving the dosage of each of the dE2F1 target genes on the dE2F1 dependent phenotype in either the eye (GMR-GAL4) or wing (ptc-GAL4) with the following abbreviations: enhanced (enh), suppressed (supp) or no effect (NE).
| dE2F1 target gene | Bloomington number and allele description | effect with GMR-GAL4 | effect with ptc-GAL4 |
|---|---|---|---|
| NetA | #12856, w1118 P{GT1}NetA, BG02298 | NE | NE |
| mus209 | #11192, cn[1] P{ry[+t7.2]=PZ}mus209[02448]/CyO; ry[506] | 20% enh | NE |
| Df31 | #10579, y[1] w[67c23]; P{w[+mC]=lacW}Df31[k05815]/CyO | NE | 20% enh |
| stg | #2500, ru1 h1 th1 st1 cu1 sr1 es stg4 ca1/TM3, Sb1 Ser1 | 40% enh | 20% enh |
| CycE | #11396, P{ry[+t7.2]=PZ}CycE[05206] cn[1]/CyO; ry[506] | 100% enh | 40-60% enh |
| dup | #7275, dup[a1]/CyO | 100% enh | 80% enh |
| ncd | #1720, Df(3R)ca[nd1], Sb[1] ss[1] Ubx[bx-34e] e[s] ncd[1] ca[nd1]/TM3 | 80% enh | NE-20enh |
| Mcm2 | #12122, ry[506] P{ry[+t7.2]=PZ}Mcm2[rL074]/TM3, Sb[1] | NE | 20% supp |
| CG7530 | #6766, y[1] w[*]; P{y[+t7.7]=Mae-UAS.6.11}CG7530[UY713] | 20% enh | 20% supp |
| Cap-G | #15944 (EP), y[1] w[67c23]; P{w[+mC] y[+mDint2]=EPgy2}CG12400[EY04850]/CyO | 20% enh | 40-60% enh |
| Orc2 | #9014 (ems), mwh[1] Orc2[1] e[1]/TM1; #15940 (EY), y1 w67c23; P{EPgy2}Orc2EY04752 | 9014: 80% supp, 15940 100% supp | 9014: 20% supp, 15940 NE |
| RnrL | #10644, y[1] w[67c23]; P{w[+mC]=lacW}RnrL[k06709]/CyO | NE | 40% enh |
| CG13345, tumbleweed | #15072, y[1] w[67c23]; P{w[+mC] y[+mDint2]=EPgy2}tum[EY01491b] P{EPgy2}shot[EY01491a] | 100% supp | NE |
| nod | #7252, nod[DR3] f[1]/C(1)DX, y[1] f[1]/Dp(1;Y)B[S] | variable phenotype | female lethal |
| CG31453 pch2 | #15536 (EP), y[1] w[67c23]; P{w[+mC] y[+mDint2]=?EPgy2}pch2[EY01788a] P{EPgy2}EY01788b | 60% enh | 20% enh |
| Hrb87F | #14414, y[1] w[67c23]; ry[506] P{y[+mDint2] w[BR.E.BR]=SUPor-P}Hrb87F[KG02089] | NE | 60% enh |
| CG15500, mod | #10312, y[1] w[1118]; P{w[+mC]=lacW}mod(mdg4)[L3101]/TM3, Ser[1] | NE | 40% enh |
| CG10712, chro | #12932, y[1]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}Chro[KG03258] ry[506]/TM3, Sb[1] Ser[1] | 40-60% enh | 20% enh |
| cdc2c | #6632, w[*]; cdc2c[2]/TM3, Sb[1] P{w[+mC]=35UZ}2 and #6636, w[*]; cdc2c[3]/TM3, Sb[1] P{w[+mC]=35UZ}2 | NE | NE |
| pav | #4384, y[1] w[1]; P{w[+mC]=lacW}64A pav[B200] th[1] st[1] cu[1] sr[1] e[s] ca[1]/TM6B, P{w[+mC]=iab-2(1.7)lacZ}6B, Tb[1] | NE | 40-60% enh |
| CG1888 | #15570 (EP), y[1] w[67c23]; P{w[+mC] y[+mDint2]=EPgy2}CG1888[EY02539] | 40% enh | 40% enh |
| Map60 | #14880, y[1]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}Map60[KG00506]/SM6a; ry[506] | 100% enh | NE |
| polo | #13941, y[1]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}polo[KG03033] ry[506]/TM3, Sb[1] Ser[1] | 13941: NE, 11543:80% enh | 13941: 20% enh, 11543: NE |
| and #11543, P{ry[+t7.2]=PZ}polo[01673] ry[506]/TM3, ry[RK] Sb[1] Ser[1] | |||
| CG6874, neo | #10264, mwh[1] P{hsneo}l(3)neo26[1] red[1] e[1]/TM3, ry[RK] Sb[1] Ser[1] | 40-60% enh | NE |
| CG9273, RPA2 | #12882, y[1] P{SUPor-P}rdgA[KG00771a]; P{SUPor-P}RPA2[KG00771b] | 50-70% enh | 40-60% enh |
| Chrac-14 | #13190, y[1] w[67c23]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}mus201[KG01051] Chrac-14[KG01051] | 100% enh | 20-40% enh |
| Hel25E | #11043, y[1] w[67c23]; P{w[+mC]=lacW}Hel25E[k11511]/CyO | 50-80% enh | 20% enh |
| CG10522, sticky | #13471, y[1]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}sti[KG01697] ry[506]/TM3, Sb[1] Ser[1] | 20-50% enh | 60-80% enh |
| dap | #11377, cn[1] P{ry[+t7.2]=PZ}dap[04454]/CyO; ry[506] | NE | NE-40% enh |
| Sd | #101498, Hex-C[nNC1] / SM1 | NE | NE |
| CG1558, Kmn1 | #11877, w[67c23] P{w[+mC]=lacW}Kmn1[G0237]/FM7c | 20% enh | 60% enh |
| DNAprim | #12108, y[1] w[*]; P{w[+mC]=lacW}DNApol-alpha60[j10B2]/TM3, Sb[1] | NE | 20% enh |
| His2Av | #11650, ry[506] P{ry[+t7.2]=PZ}His2Av[05146]/TM3, ry[RK] Sb[1] Ser[1] | 80% enh | 20% enh |
| CG3183, geminin | #11118, y[1] w[67c23]; P{w[+mC]=lacW}geminin[k14019]/CyO | 40% enh | 60 - 100% enh |
| RfC40 | #5157, bw[1]; RfC4[A18] st[1]/TM6B, Tb[1]and #5158, bw[1]; RfC4[B6] st[1]/TM6B, Tb[1] | 5157:100% supp, 5158:NE | 5157: 20% supp, 5158: NE |
| Orc5 | #3593, b[1] Orc5[2] elA[1] rd[s] pr[1] cn[1]/CyO | variable: 100% supp/NE | 60% supp |
| CG10336 | #15234, y[1]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}CG10336[KG10159]/CyO; ry[506] | 30% enh | 40% enh |
| CG5949, DNApol-delta | #17109 (EP), w[1118]; P{w[+mC]=EP}DNApol-delta[EP3292] Hip14[EP3292] | 100% supp | 20% supp |
| Rrp1 | #13700, y[1] w[67c23]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}Rrp1[KG01159] | NE | 60% enh |
| CG10489, pole 2 | #13486, y[1] w[67c23]; P{y[+mDint2] w[BR.E.BR]=SUPor-P}Pole2[KG02588] ry[506] | 60-80% enh | 40% enh |
| Bub1 | #10526, y[1] w[67c23]; P{w[+mC]=lacW}BubR1[k03113]/CyO | 60-80% enh | 20% enh |
| CG17064, mars | #19094, w1118; PBac{WH}marsf07689 | NE | NE |
| neb | #10391, y[1] w[67c23]; P{w[+mC]=lacW}neb[k05702]/CyO | variable, NE & enh | NE |
| CG7341 | #15952 (EP), y[1] w[67c23]; P{w[+mC] y[+mDint2]=EPgy2}CG32195[EY05483] CG7341[EY05483] | 20% enh | 40% enh |