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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Structure. 2011 Mar 9;19(3):418–429. doi: 10.1016/j.str.2010.12.015

Figure 5. p53 C Terminus-Binding Surface of IFI16 HIN-A Domain.

Figure 5

(A) Transparent electrostatic surface representation of IFI16 HIN-A (left) and HIN-B (right) crystal structures. White, red, and blue colors correspond to neutral, negatively, and positively charged surfaces, respectively.

(B) Agarose EMSA of p53 (82–393) with wild-type or mutant IFI16 HIN-A (left). Molar ratio of p53 to HIN-A is 1:3. Surface representation of IFI16 HIN-A (right). Residues involved in binding are colored in magenta.

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