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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Nat Struct Mol Biol. 2013 May 5;20(6):687–695. doi: 10.1038/nsmb.2562

Figure 5. Terminally unwrapped CENP-A nucleosomes and their conventional counterparts with wrapped termini are similarly phased at normal centromeres.

Figure 5

(a,b) The position of each individual CENP-A (a) or bulk nucleosome (b) along a dimerized α-satellite consensus sequence is indicated by a horizontal line. Each fragment is color-coded based on length, as indicated. (c,d) The midpoint positions of CENP-A (c) or bulk nucleosome (d) fragments along the dimer α-satellite consensus sequence. Solid vertical lines indicate the location of the 17 bp CENP-B box (B) in (a–d). (e,f) Models of the preferred positioning and MNase cleavage sites on CENP-A (e) and bulk (f) nucleosomes at normal centromeres.