Table 6.
The association of the top three genetic loci in SNP-phenotype associations HDL particle diameters response to fenofibrate with HDL subfraction concentration responses to fenofibrate
| Marker | Large HDL
|
Medium HDL
|
Small HDL
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| β (SE) | P | Q | β (SE) | P | Q | β (SE) | P | Q | |
| rs11574703 | −0.62 (0.70) | 0.38 | – | 1.85 (1.23) | 0.13 | – | 0.24 (0.69) | 0.73 | – |
| rs5001812 | −1.09 (0.91) | 0.23 | – | −0.66 (1.99 | 0.75 | – | 2.77 (0.90) | 0.002 | 0.01 |
| rs9285640 | 3.45 (5.88) | 0.56 | – | −13.27 (15.73) | 0.39 | – | 7.33 (5.85) | 0.21 | – |
HDL, high-density lipoprotein; SNPs, single nucleotide polymorphisms.