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DAF-16 target genes are differentially regulated despite over-expression of the gene encoding the DAF-2 agonist INS-7. A) Heat map of genes downstream of DAF-16 that are known to be up-regulated or down-regulated in DAF-16 mutants [25]. Changes in gene expression (log2 ratio) are shown for continuous and 8-h washout (Wash) conditions. B) Graph of ins-7 expression.
