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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Br J Nutr. 2009 Jul 9;102(10):1426–1434. doi: 10.1017/S0007114509990456

Table 5.

Gastrointestinal absorption of pinitol and [2H6]d-chiro-inositol (DCI) in rats fed Basal Diet 5755* (Mean values with their standard errors)

Dietary intake Fecal output Urinary output Total output

Mean SEM Mean SEM Mean SEM Mean SEM
Pinitol feeding
Total DCI (μmol/kg body weight per d)
 Pre-pinitol 0.09 0.02 0.07 0.02 0.48 0.31 0.54 0.31
 Pinitol, Day 1 122 7.4 1.11 0.53 26.0 1.7 27.11 0.56
 Pinitol, Day 2 0.07 0.01 0.10 0.01 0.38 0.11 0.47 0.12
[2H6]DCI Feeding
Free [2H6]DCI (nmol/kg body weight per d)
Day 1 59.1 3.6 0.15 0.1 4.0 0.4 4.2 0.2
Day 2 ND 1.0 1.0 4.3 0.1 5.3 1.1

ND, not detectable.

*

Three rats weighing 427 ± 27 g were housed individually in metabolic cages and fed Purina Basal Diet 5755 for 3 d. Pinitol, 51.5 μmol (10 mg), was given orally with urine and stools collected for the following 2 d, which were analyzed for total DCI. Then 25 nmol [2H6]DCI was given orally, followed by an additional 2 d of urine and stool collection. No [2H6]DCI was detectable before isotope administration.