Effect of rapamycin on serum parameters in db/+ and db/db mice. A) Circulating levels of triglycerides in db/+ E, db/+ R, db/db-E and db/db-R mice (n=9/group) under fed conditions. B) Free fatty acid levels in db/+ E, db/+ R, db/db-E and db/db-R mice (n=9/group) under fed conditions. C) Glucose levels in db/+ E, db/+ R, db/db-E and db/db-R mice (n=9/group) serum after 16 h without feeding. D) Insulin levels in db/+ E, db/+ R, db/db-E and db/db-R mice (n=9/group) serum under fed condition E) Serum adiponectin levels db/+ E, db/+ R, db/db-E and db/db-R mice (n=9/group) under fed condition. ***P < 0.001, **P < 0.01, *P < 0.05.